Drug Discovery 1: How Does the New SARS-CoV-2 Protease Inhibitor Block Protease Activity?
This video, provided by Digital World Biology, is from a series of tutorial videos for iCn3D, a web-based three-dimensional visualization and structural analysis platform for molecular structures. During this video, presenter Sandra Porter offers step-by-step instructions on how to view and analyze the interaction between a protease drug and SARS-CoV-2. The video guides viewers on how to:
- Select the inhibitor, the inhibitor binding site, and amino acids in the active site.
- Identify amino acids in the inhibitor binding site.
- Annotate the inhibitor binding site and the two amino acids that form the catalytic dyad.
- Identify a covalent bond to the inhibitor.
- View the binding pocket for the inhibitor.
- Identify a hydrogen bond to the inhibitor and determine which amino acid forms this bond.
This video runs 14:02 minutes in length. Additional videos in the series are available to view separately.
About this Resource
Alternate Title
Drug Discovery 1: How Does the New Severe Acute Respiratory sSyndrome Coronavirus 2 Protease Inhibitor Block Protease Activity?
Creator
Publisher
Date Issued
November 14th, 2021
Audience
Education Level
Language
Subject
GEM Subject
Relation
Series
Is Related To
Associated Files
Archived
Rights
Access Rights
Comments