Part 2: Telomeres and Telomerase in Human Stem Cells and in Cancer

This lecture from the iBioSeminars project is presented by Elizabeth Blackburn from the University of California, San Francisco Department of Biochemistry and Biophysics. It covers telomerase, a specialized ribonucleprotein reverse transcriptase, important for long-term eukaryotic cell proliferation and genomic stability because it replenishes the DNA at telomeres. Telomerase is highly active in many human malignancies, and a potential target for anti-cancer approaches. This video is the second of three parts, running 26:58 minutes and can be downloaded in QuickTime, MP4, M4V, or PDF formats. It can also be streamed on iTunes or YouTube.